LifeExtension SAM-e contains only premium, Italian Soloesse\u00ae<\/strong> , with slow and targeted release for less negative impact on digestion and for better absorption. The tablets are enterically coated so do not chew or crush them.<\/p>\n SAMe is an abbreviation for s-Adenosyl methionine, which is a substance with a high potential of donating methyl groups. Methyl groups are necessary for many other metabolic reactions, which have a positive effect on mood, depression, anxiety, as well as joints and liver.<\/p>\n SAMe is essentially the amino acid methionine, attached to the ATP molecule and traveling freely in the bloodstream. Due to the amino acid methionine, SAMe also contains sulfur and participates in transulfurization as well as aminopropylation. Most SAMe is formed and consumed in the liver. We know of over 40 methyl group transfers from SAMe. Some of these reactions lead on the one hand to glutathione and on the other to monoamine neurotransmitters (dopamine, serotonin, adrenaline \/ epinephrine).<\/p>\n SAMe originates from the methylation cycle where it can be regenerated to methionine via homocysteine and then back to s-adenosyl methionine (SAMe).<\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" It affects well-being, happiness and motivation.<\/p>\n","protected":false},"featured_media":54585,"comment_status":"open","ping_status":"closed","template":"","meta":[],"etheme_brands":[{"term_id":4697,"name":"Lifextension","slug":"lifextension","term_group":0,"term_taxonomy_id":4697,"taxonomy":"brand","description":"Lifextension provides extra quality supplements. They focus on two specific areas.\n\nRaw Materials: Unlike other supplement companies, the ingredients that go into their supplements are not chosen based on cost. Instead they are chosen based on purity, potency, and usage in successful scientific research.\n\nValidation of the Efficacy of Ingredients by Scientific Research: They use ingredients and dosages that accurately replicate the most successful results obtained in scientific studies for maximum efficacy.","parent":0,"count":5,"filter":"raw"}],"product_brand":[],"product_cat":[3784,3793,3786,3791,3787,3782,3788,3800,3783],"product_tag":[],"class_list":{"0":"post-57748","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"brand-lifextension","7":"product_cat-antioxidants","8":"product_cat-detoxification-and-liver","9":"product_cat-energy-and-motivation","10":"product_cat-immune-system","11":"product_cat-memory-and-brain-health","12":"product_cat-other","13":"product_cat-sale","14":"product_cat-sleep-insomnia","15":"product_cat-stress-management","17":"first","18":"outofstock","19":"taxable","20":"shipping-taxable","21":"purchasable","22":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product\/57748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/comments?post=57748"}],"version-history":[{"count":0,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product\/57748\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/media\/54585"}],"wp:attachment":[{"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/media?parent=57748"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/etheme_brands?post=57748"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product_brand?post=57748"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product_cat?post=57748"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/fmed.eu\/en\/wp-json\/wp\/v2\/product_tag?post=57748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}SAMe cycle<\/h3>\n